Association Between Antimicrobial Resistance in Escherichia coli Isolates from Food Animals and Blood Stream Isolates from Humans in Europe: An Ecological Study

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Association Between Antimicrobial Resistance in Escherichia coli Isolates from Food Animals and Blood Stream Isolates from Humans in Europe: An Ecological Study. / Vieira, Antonio; Collignon, Peter; Aarestrup, Frank Møller; McEwen, Scott A.; Hendriksen, Rene S.; Hald, Tine; Wegener, Henrik Caspar.

I: Foodborne Pathogens and Disease, Bind 8, Nr. 12, 2011, s. 1295-1301.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Vieira, A, Collignon, P, Aarestrup, FM, McEwen, SA, Hendriksen, RS, Hald, T & Wegener, HC 2011, 'Association Between Antimicrobial Resistance in Escherichia coli Isolates from Food Animals and Blood Stream Isolates from Humans in Europe: An Ecological Study', Foodborne Pathogens and Disease, bind 8, nr. 12, s. 1295-1301. https://doi.org/10.1089/fpd.2011.0950

APA

Vieira, A., Collignon, P., Aarestrup, F. M., McEwen, S. A., Hendriksen, R. S., Hald, T., & Wegener, H. C. (2011). Association Between Antimicrobial Resistance in Escherichia coli Isolates from Food Animals and Blood Stream Isolates from Humans in Europe: An Ecological Study. Foodborne Pathogens and Disease, 8(12), 1295-1301. https://doi.org/10.1089/fpd.2011.0950

Vancouver

Vieira A, Collignon P, Aarestrup FM, McEwen SA, Hendriksen RS, Hald T o.a. Association Between Antimicrobial Resistance in Escherichia coli Isolates from Food Animals and Blood Stream Isolates from Humans in Europe: An Ecological Study. Foodborne Pathogens and Disease. 2011;8(12):1295-1301. https://doi.org/10.1089/fpd.2011.0950

Author

Vieira, Antonio ; Collignon, Peter ; Aarestrup, Frank Møller ; McEwen, Scott A. ; Hendriksen, Rene S. ; Hald, Tine ; Wegener, Henrik Caspar. / Association Between Antimicrobial Resistance in Escherichia coli Isolates from Food Animals and Blood Stream Isolates from Humans in Europe: An Ecological Study. I: Foodborne Pathogens and Disease. 2011 ; Bind 8, Nr. 12. s. 1295-1301.

Bibtex

@article{764ef8fee5dd433a9cc724ca1ef6a14b,
title = "Association Between Antimicrobial Resistance in Escherichia coli Isolates from Food Animals and Blood Stream Isolates from Humans in Europe: An Ecological Study",
abstract = "Background: In addition to medical antimicrobial usage, the use of antimicrobials in food animals contributes to the occurrence of resistance among some bacterial species isolated from infections in humans. Recently, several studies have indicated that a large proportion of Escherichia coli causing infections in humans, especially those resistant to antimicrobials, have an animal origin.Methods: We analyzed the correlation between the prevalence of antimicrobial resistance in E. coli isolates from blood stream infections in humans and in E. coli isolates from poultry, pigs, and cattle between 2005 and 2008 for 11 countries, using available surveillance data. We also assessed the correlation between human antimicrobial usage and the occurrence of resistance in E. coli isolates from blood stream infections.Results: Strong and significant correlations between prevalences of resistance to ampicillin (r=0.94), aminoglycosides (r=0.72), third-generation cephalosporins (r=0.76), and fluoroquinolones (r=0.68) were observed for human and poultry E. coli isolates. Similar significant correlations were observed for ampicillin (r=0.91), aminoglycosides (r=0.73), and fluoroquinolone resistance (r=0.74) in pig and human isolates. In cattle isolates, only ampicillin resistance (r=0.72) was significantly correlated to human isolates. When usage of antimicrobials in humans was analyzed with antimicrobial resistance among human isolates, only correlations between fluoroquinolones (r=0.90) and third-generation cephalosporins (r=0.75) were significant.Conclusions: Resistance in E. coli isolates from food animals (especially poultry and pigs) was highly correlated with resistance in isolates from humans. This supports the hypothesis that a large proportion of resistant E. coli isolates causing blood stream infections in people may be derived from food sources.",
author = "Antonio Vieira and Peter Collignon and Aarestrup, {Frank M{\o}ller} and McEwen, {Scott A.} and Hendriksen, {Rene S.} and Tine Hald and Wegener, {Henrik Caspar}",
year = "2011",
doi = "10.1089/fpd.2011.0950",
language = "English",
volume = "8",
pages = "1295--1301",
journal = "Foodborne Pathogens and Disease",
issn = "1535-3141",
publisher = "Mary AnnLiebert, Inc. Publishers",
number = "12",

}

RIS

TY - JOUR

T1 - Association Between Antimicrobial Resistance in Escherichia coli Isolates from Food Animals and Blood Stream Isolates from Humans in Europe: An Ecological Study

AU - Vieira, Antonio

AU - Collignon, Peter

AU - Aarestrup, Frank Møller

AU - McEwen, Scott A.

AU - Hendriksen, Rene S.

AU - Hald, Tine

AU - Wegener, Henrik Caspar

PY - 2011

Y1 - 2011

N2 - Background: In addition to medical antimicrobial usage, the use of antimicrobials in food animals contributes to the occurrence of resistance among some bacterial species isolated from infections in humans. Recently, several studies have indicated that a large proportion of Escherichia coli causing infections in humans, especially those resistant to antimicrobials, have an animal origin.Methods: We analyzed the correlation between the prevalence of antimicrobial resistance in E. coli isolates from blood stream infections in humans and in E. coli isolates from poultry, pigs, and cattle between 2005 and 2008 for 11 countries, using available surveillance data. We also assessed the correlation between human antimicrobial usage and the occurrence of resistance in E. coli isolates from blood stream infections.Results: Strong and significant correlations between prevalences of resistance to ampicillin (r=0.94), aminoglycosides (r=0.72), third-generation cephalosporins (r=0.76), and fluoroquinolones (r=0.68) were observed for human and poultry E. coli isolates. Similar significant correlations were observed for ampicillin (r=0.91), aminoglycosides (r=0.73), and fluoroquinolone resistance (r=0.74) in pig and human isolates. In cattle isolates, only ampicillin resistance (r=0.72) was significantly correlated to human isolates. When usage of antimicrobials in humans was analyzed with antimicrobial resistance among human isolates, only correlations between fluoroquinolones (r=0.90) and third-generation cephalosporins (r=0.75) were significant.Conclusions: Resistance in E. coli isolates from food animals (especially poultry and pigs) was highly correlated with resistance in isolates from humans. This supports the hypothesis that a large proportion of resistant E. coli isolates causing blood stream infections in people may be derived from food sources.

AB - Background: In addition to medical antimicrobial usage, the use of antimicrobials in food animals contributes to the occurrence of resistance among some bacterial species isolated from infections in humans. Recently, several studies have indicated that a large proportion of Escherichia coli causing infections in humans, especially those resistant to antimicrobials, have an animal origin.Methods: We analyzed the correlation between the prevalence of antimicrobial resistance in E. coli isolates from blood stream infections in humans and in E. coli isolates from poultry, pigs, and cattle between 2005 and 2008 for 11 countries, using available surveillance data. We also assessed the correlation between human antimicrobial usage and the occurrence of resistance in E. coli isolates from blood stream infections.Results: Strong and significant correlations between prevalences of resistance to ampicillin (r=0.94), aminoglycosides (r=0.72), third-generation cephalosporins (r=0.76), and fluoroquinolones (r=0.68) were observed for human and poultry E. coli isolates. Similar significant correlations were observed for ampicillin (r=0.91), aminoglycosides (r=0.73), and fluoroquinolone resistance (r=0.74) in pig and human isolates. In cattle isolates, only ampicillin resistance (r=0.72) was significantly correlated to human isolates. When usage of antimicrobials in humans was analyzed with antimicrobial resistance among human isolates, only correlations between fluoroquinolones (r=0.90) and third-generation cephalosporins (r=0.75) were significant.Conclusions: Resistance in E. coli isolates from food animals (especially poultry and pigs) was highly correlated with resistance in isolates from humans. This supports the hypothesis that a large proportion of resistant E. coli isolates causing blood stream infections in people may be derived from food sources.

U2 - 10.1089/fpd.2011.0950

DO - 10.1089/fpd.2011.0950

M3 - Journal article

VL - 8

SP - 1295

EP - 1301

JO - Foodborne Pathogens and Disease

JF - Foodborne Pathogens and Disease

SN - 1535-3141

IS - 12

ER -

ID: 172808845